BARD1 Gene Polymorphisms Confer Nephroblastoma Susceptibility
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چکیده
منابع مشابه
BARD1 Gene Polymorphisms Confer Nephroblastoma Susceptibility
BRCA1-associated RING domain protein 1 (BARD1) is a tumor suppressor, which forms a heterodimer with BRCA1. Three BARD1 gene polymorphisms (rs7585356 G>A, rs6435862 T>G and rs3768716 A>G) were initially identified as high-risk neuroblastoma susceptibility loci by a previous GWAS. Because of the general tumor-suppressing function of BARD1, we hypothesized that these BARD1 gene polymorphisms migh...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2017
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2017.01.038